8AJ0: Mpro of SARS COV-2 in complex with the RK-90 inhibitor

PDB ID: 8AJ0Download
MMDB ID: 234123
PDB Deposition Date: 2022/7/27
Updated in MMDB: 2023/08
Experimental Method:
x-ray diffraction
Resolution: 2.519  Å
Source Organism:
Similar Structures:
Biological Unit for 8AJ0: dimeric; determined by author and by software (PISA)
Molecular Components in 8AJ0
Label Count Molecule
Proteins (2 molecules)
2
3c-like Proteinase Nsp5
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
(2R,3S)-3-[[(2S)-3-cyclopropyl-2-[2-oxidanylidene-3-(3-phenylpropanoylamino)pyridin-1-yl]propanoyl]amino]-N-methyl-2-oxidanyl-4-[(3S)-2-oxidanylidenepyrrolidin-3-yl]butanamide (Link to PubChem not yet available)(2R,3S)-3-[[(2S)-3-cyclopropyl-2-[2-oxidanylidene-3-(3-phenylpropanoylamino)pyridin-1-yl]propanoyl]amino]-N-methyl-2-oxidanyl-4-[(3S)-2-oxidanylidenepyrrolidin-3-yl]butanamide
2
1
CHLORIDE ION (Link to PubChem not yet available)CHLORIDE ION
3
1
SODIUM ION (Link to PubChem not yet available)SODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303