8AIZ: Mpro of SARS-CoV-2 in complex with the RK-68 inhibitor

PDB ID: 8AIZDownload
MMDB ID: 234122
PDB Deposition Date: 2022/7/27
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.992  Å
Source Organism:
Similar Structures:
Biological Unit for 8AIZ: monomeric; determined by author
Molecular Components in 8AIZ
Label Count Molecule
Protein (1 molecule)
1
Replicase Polyprotein 1AB
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
(2~{R},3~{S})-3-[[(2~{S})-3-cyclopropyl-2-[2-oxidanylidene-3-(2-phenylethanoylamino)pyridin-1-yl]propanoyl]amino]-~{N}-methyl-2-oxidanyl-4-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]butanamide(2~{R},3~{S})-3-[[(2~{S})-3-cyclopropyl-2-[2-oxidanylidene-3-(2-phenylethanoylamino)pyridin-1-yl]propanoyl]amino]-~{N}-methyl-2-oxidanyl-4-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]butanamide
2
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303