8AI4: Crystal structure of radical SAM epimerase EpeE C223A mutant from Bacillus subtilis with [4Fe-4S] clusters, S-adenosyl-L-homocysteine and RiPP peptide 5 bound

PDB ID: 8AI4Download
MMDB ID: 240913
PDB Deposition Date: 2022/7/25
Updated in MMDB: 2025/12
Experimental Method:
x-ray diffraction
Resolution: 1.75  Å
Source Organism:
Similar Structures:
Biological Unit for 8AI4: dimeric; determined by author and by software (PISA)
Molecular Components in 8AI4
Label Count Molecule
Proteins (2 molecules)
1
Radical SAM Core Domain-containing Protein
Molecule annotation
1
Putative Exported Peptide Yydf
(Gene symbol: liaD)
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
1
2
IRON/SULFUR CLUSTERIRON/SULFUR CLUSTER
2
1
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
3
8
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
4
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303