8ADJ: Poly(ADP-ribose) glycohydrolase (PARG) from Drosophila melanogaster in complex with PARG inhibitor PDD00017272

PDB ID: 8ADJDownload
MMDB ID: 231599
PDB Deposition Date: 2022/7/8
Updated in MMDB: 2023/06
Experimental Method:
x-ray diffraction
Resolution: 2.508  Å
Source Organism:
Similar Structures:
Biological Unit for 8ADJ: monomeric; determined by author
Molecular Components in 8ADJ
Label Count Molecule
Protein (1 molecule)
1
Poly(adp-ribose) Glycohydrolase
(Gene symbol: Parg)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
1
1-[(2,5-dimethylpyrazol-3-yl)methyl]-N-(1-methylcyclopropyl)-3-[(2-methyl-1,3-thiazol-5-yl)methyl]-2,4-bis(oxidanylidene)quinazoline-6-sulfonamide1-[(2,5-dimethylpyrazol-3-yl)methyl]-N-(1-methylcyclopropyl)-3-[(2-methyl-1,3-thiazol-5-yl)methyl]-2,4-bis(oxidanylidene)quinazoline-6-sulfonamide
2
2
GLYCEROLGLYCEROL
3
3
SULFATE IONSULFATE ION
4
2
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303