8A4X: Crystal structure of human Cathepsin L with covalently bound Calpain inhibitor III

PDB ID: 8A4XDownload
MMDB ID: 232335
PDB Deposition Date: 2022/6/13
Updated in MMDB: 2023/07
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 8A4X: monomeric; determined by author
Molecular Components in 8A4X
Label Count Molecule
Protein (1 molecule)
1
Cathepsin L
(Gene symbol: CTSL)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
(phenylmethyl) N-[(2S)-3-methyl-1-oxidanylidene-1-[[(2S)-1-oxidanyl-3-phenyl-propan-2-yl]amino]butan-2-yl]carbamate(phenylmethyl) N-[(2S)-3-methyl-1-oxidanylidene-1-[[(2S)-1-oxidanyl-3-phenyl-propan-2-yl]amino]butan-2-yl]carbamate
2
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
3
1
TRIETHYLENE GLYCOLTRIETHYLENE GLYCOL
4
1
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303