8A4W: Crystal structure of human cathepsin L with covalently bound Cathepsin L inhibitor IV

PDB ID: 8A4WDownload
MMDB ID: 232334
PDB Deposition Date: 2022/6/13
Updated in MMDB: 2023/07
Experimental Method:
x-ray diffraction
Resolution: 1.4  Å
Source Organism:
Similar Structures:
Biological Unit for 8A4W: monomeric; determined by author
Molecular Components in 8A4W
Label Count Molecule
Protein (1 molecule)
1
Cathepsin L
(Gene symbol: CTSL)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
N-(1-naphthylsulfonyl)-(L)-isoleucyl-(L)-tryptophanolN-(1-naphthylsulfonyl)-(L)-isoleucyl-(L)-tryptophanol
2
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
3
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
3
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303