8A23: Crystal structure of SARS-CoV-2 nsp10/nsp16 methyltransferase in complex with TO383

PDB ID: 8A23Download
MMDB ID: 231590
PDB Deposition Date: 2022/6/2
Updated in MMDB: 2023/06
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 8A23: dimeric; determined by author and by software (PISA)
Molecular Components in 8A23
Label Count Molecule
Proteins (2 molecules)
1
2'-o-methyltransferase Nsp16
Molecule annotation
1
Non-structural Protein 10
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
(2R,3R,4S,5R)-2-[4-azanyl-5-(2-quinolin-3-ylethynyl)pyrrolo[2,3-d]pyrimidin-7-yl]-5-(hydroxymethyl)oxolane-3,4-diol(2R,3R,4S,5R)-2-[4-azanyl-5-(2-quinolin-3-ylethynyl)pyrrolo[2,3-d]pyrimidin-7-yl]-5-(hydroxymethyl)oxolane-3,4-diol
2
1
GLYCEROLGLYCEROL
3
2
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303