8A1R: cryo-EM structure of thioredoxin glutathione reductase in complex with a non-competitive inhibitor

PDB ID: 8A1RDownload
MMDB ID: 231584
PDB Deposition Date: 2022/6/1
Updated in MMDB: 2023/07
Experimental Method:
electron microscopy
Resolution: 3.6  Å
Source Organism:
Similar Structures:
Biological Unit for 8A1R: dimeric; determined by author and by software (PISA)
Molecular Components in 8A1R
Label Count Molecule
Proteins (2 molecules)
2
Thioredoxin Glutathione Reductase
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
FLAVIN-ADENINE DINUCLEOTIDEFLAVIN-ADENINE DINUCLEOTIDE
2
2
(2~{R},3~{R},4~{S},5~{R})-2-[3-[[[(1~{R},2~{R},3~{R},5~{S})-2,6,6-trimethyl-3-bicyclo[3.1.1]heptanyl]amino]methyl]indol-1-yl]oxane-3,4,5-triol(2~{R},3~{R},4~{S},5~{R})-2-[3-[[[(1~{R},2~{R},3~{R},5~{S})-2,6,6-trimethyl-3-bicyclo[3.1.1]heptanyl]amino]methyl]indol-1-yl]oxane-3,4,5-triol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303