7ZYQ: Crystal Structure of EGFR-T790M/V948R in Complex with Reversible Aminopyrimidine 13

PDB ID: 7ZYQDownload
MMDB ID: 229724
PDB Deposition Date: 2022/5/25
Updated in MMDB: 2023/06
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 7ZYQ: monomeric; determined by author
Molecular Components in 7ZYQ
Label Count Molecule
Protein (1 molecule)
1
Epidermal Growth Factor Receptor
(Gene symbol: EGFR)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
phenyl 2-[[4-[4-(dimethylamino)piperidin-1-yl]-2-methoxy-phenyl]amino]-4-(1H-indol-3-yl)pyrimidine-5-carboxylatephenyl 2-[[4-[4-(dimethylamino)piperidin-1-yl]-2-methoxy-phenyl]amino]-4-(1H-indol-3-yl)pyrimidine-5-carboxylate
2
3
SULFATE IONSULFATE ION
3
2
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303