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7ZWL: Crystal structure of human STING in complex with 3',3'-c-di-(2'F,2'dAMP)

PDB ID:

MMDB ID:

239084

PDB Deposition Date:

2022/5/19

Updated in MMDB:

2023/12

Experimental Method:

x-ray diffraction

Resolution:

2 Å

Source Organism:

Homo sapiens▼

Taxonomy	Molecule
Homo sapiens	A, B
Saccharomyces cerevisiae	C

Similar Structures:

Biological Unit for 7ZWL: trimeric; determined by author and by software (PISA)

Molecular Components in 7ZWL
Label	Count	Molecule
Proteins (3 molecules)
A B	2	Stimulator of Interferon Protein
C	1	Ubiquitin-like Protein Smt3
Chemical and Non-standard biopolymers (1 molecule)
1	1	9-[(1~{R},6~{R},8~{R},9~{S},10~{R},15~{R},17~{R},18~{S})-17-(6-aminopurin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,11,13-tetraoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadecan-8-yl]purin-6-amine $9-[(1~{R},6~{R},8~{R},9~{S},10~{R},15~{R},17~{R},18~{S})-17-(6-aminopurin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,11,13-tetraoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadecan-8-yl]purin-6-amine$

* Click molecule labels to explore molecular sequence information.

Citing MMDB