7ZVK: Crystal structure of human STING in complex with 3',3'-c-(2'F,2'dAMP-IMP)

PDB ID: 7ZVKDownload
MMDB ID: 239083
PDB Deposition Date: 2022/5/16
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.83  Å
Source Organism:
Similar Structures:
Biological Unit for 7ZVK: dimeric; determined by author and by software (PISA)
Molecular Components in 7ZVK
Label Count Molecule
Proteins (2 molecules)
2
Stimulator of Interferon Protein
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
9-[(1~{R},6~{R},8~{R},9~{R},10~{R},15~{R},17~{R},18~{S})-8-(6-aminopurin-9-yl)-9-fluoranyl-3,12,18-tris(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,13-pentaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadecan-17-yl]-3~{H}-purin-6-one9-[(1~{R},6~{R},8~{R},9~{R},10~{R},15~{R},17~{R},18~{S})-8-(6-aminopurin-9-yl)-9-fluoranyl-3,12,18-tris(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,13-pentaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadecan-17-yl]-3~{H}-purin-6-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303