7ZVF: Crystal structure of human cathepsin L in complex with covalently bound CLIK148

PDB ID: 7ZVFDownload
MMDB ID: 239082
PDB Deposition Date: 2022/5/15
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.6  Å
Source Organism:
Similar Structures:
Biological Unit for 7ZVF: monomeric; determined by author
Molecular Components in 7ZVF
Label Count Molecule
Protein (1 molecule)
1
Cathepsin L
(Gene symbol: CTSL)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
2
(2S)-N-[(2S)-1-(dimethylamino)-1-oxidanylidene-3-phenyl-propan-2-yl]-2-oxidanyl-N'-(2-pyridin-2-ylethyl)butanediamide(2S)-N-[(2S)-1-(dimethylamino)-1-oxidanylidene-3-phenyl-propan-2-yl]-2-oxidanyl-N'-(2-pyridin-2-ylethyl)butanediamide
2
1
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
3
1
PENTAETHYLENE GLYCOLPENTAETHYLENE GLYCOL
4
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
5
3
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
6
1
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303