7ZSO: human purine nucleoside phosphorylase in complex with JS-554

PDB ID: 7ZSODownload
MMDB ID: 230215
PDB Deposition Date: 2022/5/7
Updated in MMDB: 2023/06
Experimental Method:
x-ray diffraction
Resolution: 1.95  Å
Source Organism:
Similar Structures:
Biological Unit for 7ZSO: trimeric; determined by author
Molecular Components in 7ZSO
Label Count Molecule
Proteins (3 molecules)
3
Purine Nucleoside Phosphorylase
(Gene symbol: PNP)
Molecule annotation
Chemicals and Non-standard biopolymers (26 molecules)
1
3
[(~{E})-2-[2-[(4-oxidanylidene-3,5-dihydropyrrolo[3,2-d]pyrimidin-7-yl)sulfanyl]-5-[2,3,4,5,6-pentakis(fluoranyl)phenoxy]phenyl]ethenyl]phosphonic acid[(~{E})-2-[2-[(4-oxidanylidene-3,5-dihydropyrrolo[3,2-d]pyrimidin-7-yl)sulfanyl]-5-[2,3,4,5,6-pentakis(fluoranyl)phenoxy]phenyl]ethenyl]phosphonic acid
2
3
GLYCEROLGLYCEROL
3
18
SULFATE IONSULFATE ION
4
2
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303