7ZRT: Crystal structure of human Urokinase-type plasminogen activator in complex with bicycle peptide inhibitor UK970

PDB ID: 7ZRTDownload
MMDB ID: 238405
PDB Deposition Date: 2022/5/5
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 7ZRT: dimeric; determined by author
Molecular Components in 7ZRT
Label Count Molecule
Proteins (2 molecules)
1
Urokinase-type Plasminogen Activator
Molecule annotation
1
Synthetic Peptide Uk970
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
2
SULFATE IONSULFATE ION
2
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
3
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
PENTAETHYLENE GLYCOLPENTAETHYLENE GLYCOL
5
1
1,3,5-tris(bromomethyl)benzene1,3,5-tris(bromomethyl)benzene
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303