7ZL3: Signal peptide mimicry primes Sec61 for client-selective inhibition

PDB ID: 7ZL3Download
MMDB ID: 228006
PDB Deposition Date: 2022/4/13
Updated in MMDB: 2023/11
Experimental Method:
electron microscopy
Resolution: 3.2  Å
Source Organism:
Similar Structures:
Molecular Components in 7ZL3
Label Count Molecule
Proteins (3 molecules)
1
Protein Transport Protein Sec61 Subunit Alpha
Molecule annotation
1
Protein Transport Protein Sec61 Subunit Gamma
Molecule annotation
1
Protein Transport Protein Sec61 Subunit Beta
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(2R)-4-cyano-2-[(2~{S})-2-(methylamino)propanoyl]oxy-butanoic acid(2R)-4-cyano-2-[(2~{S})-2-(methylamino)propanoyl]oxy-butanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303