7ZKA: ABCB1 V978C mutant (mABCB1) in the outward facing state bound to AAC

PDB ID: 7ZKADownload
MMDB ID: 229464
PDB Deposition Date: 2022/4/12
Updated in MMDB: 2023/05
Experimental Method:
electron microscopy
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 7ZKA: monomeric; determined by author and by software (PISA)
Molecular Components in 7ZKA
Label Count Molecule
Protein (1 molecule)
1
Atp-dependent Translocase Abcb1
(Gene symbol: Abcb1a)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
1
(4~{S},11~{S},18~{S})-4,11-dimethyl-18-(sulfanylmethyl)-6,13,20-trithia-3,10,17,22,23,24-hexazatetracyclo[17.2.1.1^{5,8}.1^{12,15}]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione(4~{S},11~{S},18~{S})-4,11-dimethyl-18-(sulfanylmethyl)-6,13,20-trithia-3,10,17,22,23,24-hexazatetracyclo[17.2.1.1^{5,8}.1^{12,15}]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione
2
2
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
3
2
MAGNESIUM IONMAGNESIUM ION
4
1
Lauryl Maltose Neopentyl GlycolLauryl Maltose Neopentyl Glycol
5
3
CHOLESTEROL HEMISUCCINATECHOLESTEROL HEMISUCCINATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303