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7ZIA:
Crystal structure of dCK C4S-S74E mutant in complex with UDP and the OR0634 inhibitor
PDB ID:
7ZIA
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MMDB ID:
231063
PDB Deposition Date:
2022/4/7
Updated in MMDB:
2023/06
Experimental Method:
x-ray diffraction
Resolution:
1.7 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 7ZIA: dimeric; determined by author and by software (PISA)
Molecular Components in 7ZIA
Label
Count
Molecule
Proteins (2 molecules)
A
A_1
2
Deoxycytidine Kinase
(Gene symbol:
DCK
)
Chemicals and Non-standard biopolymers (6 molecules)
1
2
URIDINE-5'-DIPHOSPHATE
2
2
2-[2-[[2-methyl-5-[6-(4-methylpiperazin-1-yl)sulfonylpyridin-3-yl]phenyl]-propyl-amino]-1,3-thiazol-4-yl]pyrimidine-4,6-diamine
3
2
SODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303