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7ZI6:
Crystal structure of dCK C4S-S74E mutant in complex with UDP and the OR0325 inhibitor
PDB ID:
7ZI6
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MMDB ID:
231059
PDB Deposition Date:
2022/4/7
Updated in MMDB:
2023/06
Experimental Method:
x-ray diffraction
Resolution:
2.1 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 7ZI6: dimeric; determined by software (PISA)
Molecular Components in 7ZI6
Label
Count
Molecule
Proteins (2 molecules)
A
A_1
2
Deoxycytidine Kinase
(Gene symbol:
DCK
)
Chemicals and Non-standard biopolymers (6 molecules)
1
2
URIDINE-5'-DIPHOSPHATE
2
2
4-(4-azanylpyrimidin-2-yl)-N-[2-methyl-5-[4-[2-(4-methylpiperazin-1-yl)ethyl]phenyl]phenyl]-1,3-thiazol-2-amine
3
2
SODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303