7ZHN: Crystal structure of TTBK1 in complex with AMG28

PDB ID: 7ZHNDownload
MMDB ID: 229176
PDB Deposition Date: 2022/4/6
Updated in MMDB: 2023/05
Experimental Method:
x-ray diffraction
Resolution: 1.85  Å
Source Organism:
Similar Structures:
Biological Unit for 7ZHN: monomeric; determined by author and by software (PISA)
Molecular Components in 7ZHN
Label Count Molecule
Protein (1 molecule)
1
Tau-tubulin Kinase 1
(Gene symbol: TTBK1)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
1
PHOSPHATE IONPHOSPHATE ION
2
6
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
1
4-(2-amino-5,6,7,8-tetrahydropyrimido[4',5':3,4]cyclohepta[1,2-b]indol-11-yl)-2-methylbut-3-yn-2-ol4-(2-amino-5,6,7,8-tetrahydropyrimido[4',5':3,4]cyclohepta[1,2-b]indol-11-yl)-2-methylbut-3-yn-2-ol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303