7Z5N: Crystal structure of DYRK1A in complex with CX-4945

PDB ID: 7Z5NDownload
MMDB ID: 227998
PDB Deposition Date: 2022/3/9
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.77  Å
Source Organism:
Similar Structures:
Biological Unit for 7Z5N: monomeric; determined by author
Molecular Components in 7Z5N
Label Count Molecule
Protein (1 molecule)
1
Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1A
(Gene symbol: DYRK1A)
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
1
5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid
2
5
SULFATE IONSULFATE ION
3
2
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
4
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
5
4
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303