7Z4S: Crystal structure of SARS-CoV-2 Mpro in complex with cyclic peptide GM4 including unnatural amino acids

PDB ID: 7Z4SDownload
MMDB ID: 238662
PDB Deposition Date: 2022/3/4
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Severe acute respiratory syndrome coronavirus 2▼
Similar Structures:
Biological Unit for 7Z4S: tetrameric; determined by author and by software (PISA)
Molecular Components in 7Z4S
Label Count Molecule
Proteins (4 molecules)
2
3c-like Proteinase Nsp5
Molecule annotation
2
Macrocyclic Peptide Inhibitor
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
2
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
TRIETHYLENE GLYCOLTRIETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303