7YUZ: Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor AP8784

PDB ID: 7YUZDownload
MMDB ID: 233199
PDB Deposition Date: 2022/8/18
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.878  Å
Source Organism:
Similar Structures:
Biological Unit for 7YUZ: dimeric; determined by author and by software (PISA)
Molecular Components in 7YUZ
Label Count Molecule
Protein (1 molecule)
1
Isoform 2B of Gtpase Kras
(Gene symbol: KRAS)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
I
1
AP8784
1
1
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
IODIDE IONIODIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303