7YL2: Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor Y07004

PDB ID: 7YL2Download
MMDB ID: 233195
PDB Deposition Date: 2022/7/25
Updated in MMDB: 2023/08
Experimental Method:
x-ray diffraction
Resolution: 1.62  Å
Source Organism:
Similar Structures:
Biological Unit for 7YL2: monomeric; determined by author and by software (PISA)
Molecular Components in 7YL2
Label Count Molecule
Protein (1 molecule)
1
Bromodomain-containing Protein 4
(Gene symbol: BRD4)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
N-(1-ethyl-2-oxidanylidene-3H-indol-5-yl)cyclohexanesulfonamideN-(1-ethyl-2-oxidanylidene-3H-indol-5-yl)cyclohexanesulfonamide
2
1
GLYCEROLGLYCEROL
3
1
NITRATE IONNITRATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303