7YIY: Cryo-EM structure of SPT-ORMDL3 complex

PDB ID: 7YIYDownload
MMDB ID: 232311
PDB Deposition Date: 2022/7/18
Updated in MMDB: 2023/07
Experimental Method:
electron microscopy
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 7YIY: pentameric; determined by author
Molecular Components in 7YIY
Label Count Molecule
Proteins (5 molecules)
1
Serine Palmitoyltransferase 2
(Gene symbol: SPTLC2)
Molecule annotation
1
Serine Palmitoyltransferase 1
(Gene symbol: SPTLC1)
Molecule annotation
1
Orm1-like Protein 3
(Gene symbol: ORMDL3)
Molecule annotation
1
Serine Palmitoyltransferase Small Subunit a
(Gene symbol: SPTSSA)
Molecule annotation
1
Serine Palmitoyltransferase 1
(Gene symbol: SPTLC1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
PYRIDOXAL-5'-PHOSPHATEPYRIDOXAL-5'-PHOSPHATE
2
1
N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamideN-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303