7YFC: Cryo-EM structure of the histamine-bound histamine H4 receptor and Gq complex

PDB ID: 7YFCDownload
MMDB ID: 237033
PDB Deposition Date: 2022/7/8
Updated in MMDB: 2023/11
Experimental Method:
electron microscopy
Resolution: 3  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 7YFC: hexameric; determined by author
Molecular Components in 7YFC
Label Count Molecule
Proteins (6 molecules)
1
Engineered G-alpha-q
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Scfv16
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Nb35
Molecule annotation
1
Histamine H4 Receptor
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
HISTAMINEHISTAMINE
2
1
CHOLESTEROLCHOLESTEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303