7YDX: Crystal structure of human RIPK1 kinase domain in complex with compound RI-962

PDB ID: 7YDXDownload
MMDB ID: 229133
PDB Deposition Date: 2022/7/4
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.642  Å
Source Organism:
Similar Structures:
Biological Unit for 7YDX: dimeric; determined by author and by software (PISA)
Molecular Components in 7YDX
Label Count Molecule
Proteins (2 molecules)
2
Receptor-interacting Serine/threonine-protein Kinase 1
(Gene symbol: RIPK1)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
2
1-methyl-5-[2-(2-methylpropanoylamino)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-N-[(1S)-1-phenylethyl]indole-3-carboxamide1-methyl-5-[2-(2-methylpropanoylamino)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-N-[(1S)-1-phenylethyl]indole-3-carboxamide
2
7
IODIDE IONIODIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303