7Y7Z: Cryo-EM structure of human GABA transporter GAT1 bound with tiagabine in NaCl solution in an inward-open state at 3.2 angstrom

PDB ID: 7Y7ZDownload
MMDB ID: 229446
PDB Deposition Date: 2022/6/22
Updated in MMDB: 2023/12
Experimental Method:
electron microscopy
Resolution: 3.2  Å
Source Organism:
Similar Structures:
Biological Unit for 7Y7Z: monomeric; determined by author
Molecular Components in 7Y7Z
Label Count Molecule
Protein (1 molecule)
1
Sodium- and Chloride-dependent Gaba Transporter 1
(Gene symbol: SLC6A1)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
TiagabineTiagabine
2
3
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
3
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303