7Y35: Cryo-EM structure of the Abaloparatide-bound human PTH1R-Gs complex

PDB ID: 7Y35Download
MMDB ID: 232274
PDB Deposition Date: 2022/6/9
Updated in MMDB: 2023/07
Experimental Method:
electron microscopy
Resolution: 2.9  Å
Source Organism:
synthetic construct▼
Similar Structures:
Molecular Components in 7Y35
Label Count Molecule
Proteins (6 molecules)
1
Parathyroid Hormone/parathyroid Hormone-related Peptide Receptor
Molecule annotation
1
Abaloparatide
Molecule annotation
1
Isoform Gnas-2 of Guanine Nucleotide-binding Protein G(s) Subunit Alpha Isoforms Short
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Nanobody 35
Molecule annotation
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303