7Y0F: Crystal structure of TMPRSS2 in complex with UK-371804

PDB ID: 7Y0FDownload
MMDB ID: 239308
PDB Deposition Date: 2022/6/4
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 7Y0F: dimeric; determined by author and by software (PISA)
Molecular Components in 7Y0F
Label Count Molecule
Proteins (2 molecules)
1
Transmembrane Protease Serine 2 Catalytic Chain
(Gene symbol: TMPRSS2)
Molecule annotation
1
Transmembrane Protease Serine 2 Catalytic Chain
(Gene symbol: TMPRSS2)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
CALCIUM IONCALCIUM ION
3
1
2-[(1-carbamimidamido-4-chloranyl-isoquinolin-7-yl)sulfonylamino]-2-methyl-propanoic acid2-[(1-carbamimidamido-4-chloranyl-isoquinolin-7-yl)sulfonylamino]-2-methyl-propanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303