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7XZH:
Cryo-EM structure of human LRRC8A
PDB ID:
7XZH
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MMDB ID:
231033
PDB Deposition Date:
2022/6/2
Updated in MMDB:
2023/06
Experimental Method:
electron microscopy
Resolution:
2.78 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 7XZH: hexameric; determined by author
Molecular Components in 7XZH
Label
Count
Molecule
Proteins (6 molecules)
A
B
C
D
E
F
6
Volume-regulated Anion Channel Subunit Lrrc8a
(Gene symbol:
LRRC8A
)
Chemicals and Non-standard biopolymers (24 molecules)
1
6
O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine
2
6
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
3
12
CHOLESTEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303