7XXI: Cryo-EM structure of the purinergic receptor P2Y12R in complex with 2MeSADP and Gi

PDB ID: 7XXIDownload
MMDB ID: 231025
PDB Deposition Date: 2022/5/30
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 3  Å
Source Organism:
Similar Structures:
Biological Unit for 7XXI: tetrameric; determined by author
Molecular Components in 7XXI
Label Count Molecule
Proteins (4 molecules)
1
P2Y Purinoceptor 12
(Gene symbol: P2RY12)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-2
(Gene symbol: GNAI2)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
(Gene symbol: GNB1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
(Gene symbol: GNG2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-(methylsulfanyl)adenosine 5'-(trihydrogen diphosphate)2-(methylsulfanyl)adenosine 5'-(trihydrogen diphosphate)
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303