7XTX: High resolution crystal structure of human macrophage migration inhibitory factor in complex with methotrexate

PDB ID: 7XTXDownload
MMDB ID: 230390
PDB Deposition Date: 2022/5/18
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.28  Å
Source Organism:
Similar Structures:
Biological Unit for 7XTX: trimeric; determined by author and by software (PISA)
Molecular Components in 7XTX
Label Count Molecule
Proteins (3 molecules)
3
Macrophage Migration Inhibitory Factor
(Gene symbol: MIF)
Molecule annotation
Chemicals and Non-standard biopolymers (19 molecules)
1
4
SULFATE IONSULFATE ION
2
11
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
3
ISOPROPYL ALCOHOLISOPROPYL ALCOHOL
4
1
N-(4-{[(2,4-DIAMINOPTERIDIN-1-IUM-6-YL)METHYL](METHYL)AMINO}BENZOYL)-L-GLUTAMIC ACIDN-(4-{[(2,4-DIAMINOPTERIDIN-1-IUM-6-YL)METHYL](METHYL)AMINO}BENZOYL)-L-GLUTAMIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303