7XMK: Crystal structure of human RIPK1 kinase domain in complex with compound SKLB923

PDB ID: 7XMKDownload
MMDB ID: 229437
PDB Deposition Date: 2022/4/26
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.376  Å
Source Organism:
Similar Structures:
Biological Unit for 7XMK: dimeric; determined by author and by software (PISA)
Molecular Components in 7XMK
Label Count Molecule
Proteins (2 molecules)
2
Receptor-interacting Serine/threonine-protein Kinase 1
(Gene symbol: RIPK1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
IODIDE IONIODIDE ION
2
2
5-[2-(cyclopropylcarbonylamino)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-N-[(1S)-1-(3-fluorophenyl)ethyl]-1-methyl-indole-3-carboxamide5-[2-(cyclopropylcarbonylamino)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-N-[(1S)-1-(3-fluorophenyl)ethyl]-1-methyl-indole-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303