7XHK: High-resolution X-ray cocrystal structure of USP7 in complex with LX04-46

PDB ID: 7XHKDownload
MMDB ID: 231511
PDB Deposition Date: 2022/4/8
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 7XHK: monomeric; determined by author
Molecular Components in 7XHK
Label Count Molecule
Protein (1 molecule)
1
Ubiquitin Carboxyl-terminal Hydrolase 7
(Gene symbol: USP7)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
~{N}-[[4-[6-[[1-[[2-chloranyl-4-(furan-2-yl)phenyl]methyl]-4-oxidanyl-piperidin-4-yl]methyl]-2-methyl-7-oxidanylidene-pyrazolo[4,3-d]pyrimidin-3-yl]phenyl]methyl]methanamide~{N}-[[4-[6-[[1-[[2-chloranyl-4-(furan-2-yl)phenyl]methyl]-4-oxidanyl-piperidin-4-yl]methyl]-2-methyl-7-oxidanylidene-pyrazolo[4,3-d]pyrimidin-3-yl]phenyl]methyl]methanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303