7XDG: Cryo-EM structures of human mitochondrial NAD(P)+-dependent malic enzyme in a ternary complex with NAD+ and allosteric inhibitor MDSA

PDB ID: 7XDGDownload
MMDB ID: 228315
PDB Deposition Date: 2022/3/27
Updated in MMDB: 2024/07
Experimental Method:
electron microscopy
Resolution: 2.84  Å
Source Organism:
Similar Structures:
Biological Unit for 7XDG: tetrameric; determined by author
Molecular Components in 7XDG
Label Count Molecule
Proteins (4 molecules)
4
Nad-dependent Malic Enzyme, Mitochondrial
(Gene symbol: ME2)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
8
NICOTINAMIDE-ADENINE-DINUCLEOTIDENICOTINAMIDE-ADENINE-DINUCLEOTIDE
2
4
5-[(3-carboxy-4-oxidanyl-phenyl)methyl]-2-oxidanyl-benzoic acid5-[(3-carboxy-4-oxidanyl-phenyl)methyl]-2-oxidanyl-benzoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303