7X3P: Crystal structure of human SIRT5 in complex with diazirine inhibitor 9

PDB ID: 7X3PDownload
MMDB ID: 235041
PDB Deposition Date: 2022/3/1
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 1.56  Å
Source Organism:
Similar Structures:
Biological Unit for 7X3P: monomeric; determined by author
Molecular Components in 7X3P
Label Count Molecule
Protein (1 molecule)
1
Nad-dependent Protein Deacylase Sirtuin-5, Mitochondrial
(Gene symbol: SIRT5)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
5-[[(5~{S})-6-[[(1~{S})-1-(4-hydroxyphenyl)-2-oxidanylidene-2-(prop-2-ynylamino)ethyl]amino]-6-oxidanylidene-5-[[4-[3-(trifluoromethyl)-1,2-diazirin-3-yl]phenyl]carbonylamino]hexyl]amino]-5-sulfanylidene-pentanoic acid5-[[(5~{S})-6-[[(1~{S})-1-(4-hydroxyphenyl)-2-oxidanylidene-2-(prop-2-ynylamino)ethyl]amino]-6-oxidanylidene-5-[[4-[3-(trifluoromethyl)-1,2-diazirin-3-yl]phenyl]carbonylamino]hexyl]amino]-5-sulfanylidene-pentanoic acid
2
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
3
1
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303