7W7O: The crystal structure of human Calpain-1 protease core in complex with 14a

PDB ID: 7W7ODownload
MMDB ID: 231010
PDB Deposition Date: 2021/12/6
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.59  Å
Source Organism:
Similar Structures:
Biological Unit for 7W7O: monomeric; determined by author and by software (PISA)
Molecular Components in 7W7O
Label Count Molecule
Protein (1 molecule)
1
Calpain-1 Catalytic Subunit
(Gene symbol: CAPN1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
N-[(2S)-3-(4-fluorophenyl)-1-oxidanylidene-1-[[(2S,3S)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-1-benzofuran-2-carboxamideN-[(2S)-3-(4-fluorophenyl)-1-oxidanylidene-1-[[(2S,3S)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-1-benzofuran-2-carboxamide
2
1
HYDROSULFURIC ACIDHYDROSULFURIC ACID
3
2
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303