7V0R: Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -ppcpG(2 ,5 )pA

PDB ID: 7V0RDownload
MMDB ID: 229935
PDB Deposition Date: 2022/5/10
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.51  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 7V0R: hexameric; determined by author and by software (PISA)
Molecular Components in 7V0R
Label Count Molecule
Proteins (2 molecules)
2
Cyclic Gmp-amp Synthase
Molecule annotation
Nucleotides(4 molecules)
4
Palindromic Dna18
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
[(2~{R},3~{R},4~{R},5~{R})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-[[oxidanyl(phosphonooxy)phosphoryl]methyl]phosphinic acid[(2~{R},3~{R},4~{R},5~{R})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-[[oxidanyl(phosphonooxy)phosphoryl]methyl]phosphinic acid
2
4
MAGNESIUM IONMAGNESIUM ION
3
2
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303