7UYZ: Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG

PDB ID: 7UYZDownload
MMDB ID: 229932
PDB Deposition Date: 2022/5/7
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.49  Å
Source Organism:
DNA molecule▼
Similar Structures:
Biological Unit for 7UYZ: hexameric; determined by author and by software (PISA)
Molecular Components in 7UYZ
Label Count Molecule
Proteins (2 molecules)
2
Cyclic Gmp-amp Synthase
Molecule annotation
Nucleotides(4 molecules)
4
Palindromic Dna18
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
4
MAGNESIUM IONMAGNESIUM ION
2
2
ZINC IONZINC ION
3
2
GUANOSINE-5'-MONOPHOSPHATEGUANOSINE-5'-MONOPHOSPHATE
4
2
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303