7UE8: PANK3 complex structure with compound PZ-3890

PDB ID: 7UE8Download
MMDB ID: 228270
PDB Deposition Date: 2022/3/21
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.01  Å
Source Organism:
Similar Structures:
Biological Unit for 7UE8: dimeric; determined by author and by software (PISA)
Molecular Components in 7UE8
Label Count Molecule
Proteins (2 molecules)
2
Pantothenate Kinase 3
(Gene symbol: PANK3)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
2
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
2
2
MAGNESIUM IONMAGNESIUM ION
3
2
1-[4-(6-chloropyridazin-3-yl)piperazin-1-yl]-2-(4-cyclopropyl-3-fluorophenyl)ethan-1-one1-[4-(6-chloropyridazin-3-yl)piperazin-1-yl]-2-(4-cyclopropyl-3-fluorophenyl)ethan-1-one
4
2
ACETATE IONACETATE ION
5
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303