7U8Y: TREX1 Structural Studies Capture Small Molecule Inhibition and Implicate Novel DNA Dynamics

PDB ID: 7U8YDownload
MMDB ID: 227742
PDB Deposition Date: 2022/3/9
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.22  Å
Source Organism:
Similar Structures:
Biological Unit for 7U8Y: dimeric; determined by author and by software (PISA)
Molecular Components in 7U8Y
Label Count Molecule
Proteins (2 molecules)
2
Three-prime Repair Exonuclease 1
(Gene symbol: Trex1)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
ALIZARIN REDALIZARIN RED
2
4
MANGANESE (II) IONMANGANESE (II) ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303