7U5V: Crystal structure of the Mixed Lineage Leukaemia (MLL1) SET Domain with the cofactor product S-Adenosylhomocysteine and Borealin peptide

PDB ID: 7U5VDownload
MMDB ID: 236043
PDB Deposition Date: 2022/3/2
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.59  Å
Source Organism:
Similar Structures:
Biological Unit for 7U5V: dimeric; determined by author and by software (PISA)
Molecular Components in 7U5V
Label Count Molecule
Proteins (2 molecules)
1
Histone-lysine N-methyltransferase 2A
(Gene symbol: KMT2A)
Molecule annotation
1
Borealin
(Gene symbol: CDCA8)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
ZINC IONZINC ION
2
1
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303