7TRS: Human M4 muscarinic acetylcholine receptor complex with Gi1 and the endogenous agonist acetylcholine

PDB ID: 7TRSDownload
MMDB ID: 230155
PDB Deposition Date: 2022/1/30
Updated in MMDB: 2023/05
Experimental Method:
electron microscopy
Resolution: 2.8  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 7TRS: pentameric; determined by author
Molecular Components in 7TRS
Label Count Molecule
Proteins (5 molecules)
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Antibody Fragment Scfv16
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1
Molecule annotation
1
Muscarinic Acetylcholine Receptor M4
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
ACETYLCHOLINEACETYLCHOLINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303