7SXG: BIO-8546 bound GSK3alpha-axin complex

PDB ID: 7SXGDownload
MMDB ID: 231490
PDB Deposition Date: 2021/11/23
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 7SXG: dimeric; determined by author and by software (PISA)
Molecular Components in 7SXG
Label Count Molecule
Proteins (2 molecules)
1
Glycogen Synthase Kinase-3 Alpha
(Gene symbol: GSK3A)
Molecule annotation
1
Axin Peptide
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(4S,5R,8R)-4-ethyl-8-fluoro-4-[3-(3-fluoro-5-methoxypyridin-4-yl)phenyl]-7,7-dimethyl-4,5,6,7,8,9-hexahydro-2H-pyrazolo[3,4-b]quinolin-5-ol(4S,5R,8R)-4-ethyl-8-fluoro-4-[3-(3-fluoro-5-methoxypyridin-4-yl)phenyl]-7,7-dimethyl-4,5,6,7,8,9-hexahydro-2H-pyrazolo[3,4-b]quinolin-5-ol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303