7SXF: BIO-2895 (BRD0705) bound GSK3alpha-axin complex

PDB ID: 7SXFDownload
MMDB ID: 231489
PDB Deposition Date: 2021/11/23
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.94  Å
Source Organism:
Similar Structures:
Biological Unit for 7SXF: dimeric; determined by author and by software (PISA)
Molecular Components in 7SXF
Label Count Molecule
Proteins (2 molecules)
1
Glycogen Synthase Kinase-3 Alpha
(Gene symbol: GSK3A)
Molecule annotation
1
Axin Peptide
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
(4~{S})-4-ethyl-7,7-dimethyl-4-phenyl-2,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one(4~{S})-4-ethyl-7,7-dimethyl-4-phenyl-2,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one
2
1
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303