7SQA: PPAR gamma LBD bound to SR10221 and SMRT corepressor motif

PDB ID: 7SQADownload
MMDB ID: 229915
PDB Deposition Date: 2021/11/5
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.499  Å
Source Organism:
Similar Structures:
Biological Unit for 7SQA: dimeric; determined by author and by software (PISA)
Molecular Components in 7SQA
Label Count Molecule
Proteins (2 molecules)
1
Peroxisome Proliferator-activated Receptor Gamma
(Gene symbol: PPARG)
Molecule annotation
1
Nuclear Receptor Corepressor 2
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(2S)-2-{5-[(5-{[(1S)-1-(4-tert-butylphenyl)ethyl]carbamoyl}-2,3-dimethyl-1H-indol-1-yl)methyl]-2-chlorophenoxy}propanoic acid(2S)-2-{5-[(5-{[(1S)-1-(4-tert-butylphenyl)ethyl]carbamoyl}-2,3-dimethyl-1H-indol-1-yl)methyl]-2-chlorophenoxy}propanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303