7RS3: Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with DMERI-29

PDB ID: 7RS3Download
MMDB ID: 206426
PDB Deposition Date: 2021/8/10
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.84  Å
Source Organism:
Similar Structures:
Biological Unit for 7RS3: dimeric; determined by author and by software (PISA)
Molecular Components in 7RS3
Label Count Molecule
Proteins (2 molecules)
2
Estrogen Receptor
(Gene symbol: ESR1)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
(1S,2R,4S)-6-[4-(benzyloxy)phenyl]-5-(4-hydroxyphenyl)-N-(4-methoxyphenyl)-N-(2,2,2-trifluoroethyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide(1S,2R,4S)-6-[4-(benzyloxy)phenyl]-5-(4-hydroxyphenyl)-N-(4-methoxyphenyl)-N-(2,2,2-trifluoroethyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide
2
1
TYROSINETYROSINE
3
1
SERINESERINE
4
1
CYSTEINECYSTEINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303