7PE9: cryo-EM structure of DEPTOR bound to human mTOR complex 2, DEPt-bound subset local refinement

PDB ID: 7PE9Download
MMDB ID: 206400
PDB Deposition Date: 2021/8/9
Updated in MMDB: 2025/12
Experimental Method:
electron microscopy
Resolution: 3.7  Å
Source Organism:
Similar Structures:
Biological Unit for 7PE9: pentameric; determined by author and by software (PISA)
Molecular Components in 7PE9
Label Count Molecule
Proteins (5 molecules)
1
Serine/threonine-protein Kinase Mtor
(Gene symbol: MTOR)
Molecule annotation
1
Target of Rapamycin Complex Subunit Lst8
(Gene symbol: MLST8)
Molecule annotation
1
Rapamycin-insensitive Companion of Mtor
(Gene symbol: RICTOR)
Molecule annotation
1
Target of Rapamycin Complex 2 Subunit Mapkap1
(Gene symbol: MAPKAP1)
Molecule annotation
1
DEP Domain-containing Mtor-interacting Protein
(Gene symbol: DEPTOR)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
INOSITOL HEXAKISPHOSPHATEINOSITOL HEXAKISPHOSPHATE
2
1
ZINC IONZINC ION
3
1
ACETYL GROUPACETYL GROUP
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303