7OZ7: Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, L84

PDB ID: 7OZ7Download
MMDB ID: 204603
PDB Deposition Date: 2021/6/26
Updated in MMDB: 2022/11
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 7OZ7: dimeric; determined by author and by software (PISA)
Molecular Components in 7OZ7
Label Count Molecule
Proteins (2 molecules)
2
Dipeptidyl Peptidase 8
(Gene symbol: DPP8)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
~{N}-[3-[[4-[(4-bromophenyl)methyl]piperazin-1-yl]methyl]phenyl]-2-ethyl-2-methanoyl-butanamide~{N}-[3-[[4-[(4-bromophenyl)methyl]piperazin-1-yl]methyl]phenyl]-2-ethyl-2-methanoyl-butanamide
2
2
trimethylamine oxidetrimethylamine oxide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303