7OUG: STLV-1 intasome:B56 in complex with the strand-transfer inhibitor raltegravir

PDB ID: 7OUGDownload
MMDB ID: 205725
PDB Deposition Date: 2021/6/11
Updated in MMDB: 2021/10
Experimental Method:
electron microscopy
Resolution: 3.1  Å
Source Organism:
Simian T-lymphotropic virus 1▼
Similar Structures:
Biological Unit for 7OUG: decameric; determined by author
Molecular Components in 7OUG
Label Count Molecule
Proteins (6 molecules)
4
Integrase
Molecule annotation
2
Isoform 3 of PC4 and Sfrs1-interacting Protein,isoform Gamma-2 of Serine/threonine-protein Phosphatase 2A 56 KDA Regulatory Subunit Gamma Isoform
Molecule annotation
Nucleotides(4 molecules)
2
DNA (5'-d(*ap*cp*tp*gp*tp*gp*tp*tp*tp*gp*gp*cp*gp*cp*tp*tp*cp*tp*cp*tp*c)-3')
Molecule annotation
2
DNA (5'-d(*gp*ap*gp*ap*gp*ap*ap*gp*cp*gp*cp*cp*ap*ap*ap*cp*ap*cp*a)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
4
ZINC IONZINC ION
2
4
MAGNESIUM IONMAGNESIUM ION
3
2
N-(4-fluorobenzyl)-5-hydroxy-1-methyl-2-(1-methyl-1-{[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino}ethyl)-6-oxo-1,6-di hydropyrimidine-4-carboxamideN-(4-fluorobenzyl)-5-hydroxy-1-methyl-2-(1-methyl-1-{[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino}ethyl)-6-oxo-1,6-di hydropyrimidine-4-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303